Just reverse the logic/condition in IF clause
Private Sub TestIF()
Dim m2 As Integer, MyLastRow2 As Integer
MyLastRow2 = 7
For m2 = 2 To MyLastRow2
If Not (Worksheets("CRE ATW").Cells(m2, "E").Value = "Signalling" Or _
Worksheets("CRE ATW").Cells(m2, "E").Value = "Telecoms") Then
Worksheets("CRE ATW").Cells(m2, "A").ClearContents
End If
Next m2
End Sub
Thank you.