Thanks for all comments that I learned from and I edited the query to be:

 UPDATE DBPaths SET Path_Image = 'E:\pics2024' +  RIGHT(Path_Image, (CHARINDEX('\', REVERSE(Path_Image)) )) from DBPaths 

The result will be :

 Path_Image
 E:\pics2024\1.png
 E:\pics2024\22.jpg
 E:\pics2024\947141.JPG