A nice Python counterpart to the Java owlapi is owlapy (note the y at the end): https://github.com/dice-group/owlapy

It has the following features according to its documentation (https://dice-group.github.io/owlapy/usage/main.html#what-is-owlapy):

• Create, manipulate and save Ontologies.
• Retrieving information from the signature of the ontology.
• Reasoning over ontology.
• Represent every notation in OWL 2 Structural Specification and Functional-Style Syntax including:
  • Entities, Literals, and Anonymous Individuals
  • Property Expressions
  • Data Ranges
  • Class Expressions
  • Axioms
  • Annotations
• Construct complex class expressions.
• Provide interfaces for OWL Ontology, Ontology manager and Reasoner.
• Convert owl expression to SPARQL queries.
• Render owl expression to Description Logics or Manchester syntax.
• Parse Description Logics or Manchester expression to owl expression.