I have found a way to make it work in regional in europe, by adding this to my config:
CALLER_ID = "urn:botframework:azure"
OAUTH_URL = "https://europe.token.botframework.com/"
TO_CHANNEL_FROM_BOT_LOGIN_URL = f"https://login.microsoftonline.com/{APP_TENANTID}/oauth2/v2.0/token"
TO_CHANNEL_FROM_BOT_OAUTH_SCOPE = "https://api.botframework.com/.default"
TO_BOT_FROM_CHANNEL_TOKEN_ISSUER = "https://api.botframework.com"
TO_BOT_FROM_CHANNEL_OPENID_METADATA_URL = "https://login.botframework.com/v1/.well-known/openidconfiguration"
TO_BOT_FROM_EMULATOR_OPENID_METADATA_URL = "https://login.microsoftonline.com/common/v2.0/.well-known/openid-configuration"
VALIDATE_AUTHORITY = True
source: