To integrate many TYPO3 extensions you need to integrate the TypoScript settings. Mostly done in the "Template" module, from v13 on you can add TypoScript per site in the Site Sets.

Documentation:

• Template module: https://docs.typo3.org/m/typo3/reference-typoscript/main/en-us/UsingSetting/Entering.html#static-includes
• Site sets: https://docs.typo3.org/c/typo3/cms-core/main/en-us/Changelog/13.1/Feature-103437-IntroduceSiteSets.html