For ticks on both side a workaround would be to draw the line again from other end

create_ruler_in(x1, y1, x2, y2,title="",tick_dis=10)
create_ruler_in(x2, y2, x1, y1,title="",tick_dis=10)

And for distance set

ruler.SetRulerMode(True)

ruler.SetRulerDistance(#distance you need)