I have the same problem, and I think it is caused by the fact that I had Spyder installed separately before I installed Anaconda. The solution for me was to select the anaconda python path. In Spyder, click on the pyhton icon and make sure it points to anaconda and un-check the separate spyder installation root.
Then go to file and from the drop down click restart to restart the Sypedr application. This seems to solve the problem.