To learn how to make socket.io work with cPanel, check out the following post from cPanel. It explains the steps you need to follow to get it up and running.

https://support.cpanel.net/hc/en-us/articles/1500000615942-Getting-Started-with-Socket-IO-and-NodeJS-10-on-cPanel

I just tested it on a cPanel and CloudLinux server, and it worked perfectly, even with Node.js version 16.