Some users are getting a Bad file descriptor error when uploading files to Google Drive. The uploads mostly work, but this error happens for a few users. OP finds out that the error is nothing to do with Google Drive but more on the library they are using.
Based on my experience, this error is usually related to file access. As mentioned in the comments, it can occur when the program attempts to access a file that either doesn't exist or for which it lacks the necessary permissions.
@James Allen clarified that the problem isn't with Google Drive, but with the misleading error message from the http library being used.