Use srlua. I recently packaged srlua in the luaToExe project (https://github.com/Water-Run/luaToEXE) to make it easier to use. It includes a command line application exelua and a python library lua-to-exe. Just

pip install lua-to-exe

and call the GUI method to use the graphical interface.

import lua_to_exe
lua_to_exe.gui()

(If you find it useful, please give it a star, it's an incentive to do a little work :))