To configure dependencies for hybrid web and mobile apps in a monorepo using tools like Turborepo, start by organizing your project into clearly defined packages—such as apps/web, apps/mobile, and packages/ui. Use a shared package.json to manage common dependencies, and install tools like Yarn Workspaces or npm workspaces for workspace linking. Separate platform-specific code when necessary, and keep reusable components in shared packages. Turborepo helps speed up builds and caching across projects. Maintain clean dependency boundaries, use aliases for module resolution, and configure build pipelines per app for efficient development across web and mobile platforms.