ClickOnce allows two "Install Modes": available online only, available offline as well.
With offline mode, the ActivationUri is not available. Instead, you can access:
AppDomain.CurrentDomain.SetupInformation.ActivationArguments.ActivationData
Launch the offline app by referencing the shortcut from a command line in this form:
"%userprofile%\Desktop\My App Name.appref-ms" arg1,arg2,arg3
Further explanation can be found: