You can try AutoHotKey

For AutoHotKey v2:

; TOUCHPAD on off alt+1
touchpadEnabled:=True
!1::{
    global touchpadEnabled
    touchpadEnabled:=!touchpadEnabled
    Run "SystemSettingsAdminFlows.exe EnableTouchPad " touchpadEnabled
    MsgBox (touchpadEnabled?'FOO':'BAR') ' - ' touchpadEnabled
}