I have Theano working with CUDA 12 and Numpy 1.26.4, all very new. I've been "sort-of" maintaining Theano, and have provided all the changes to https://github.com/pbaggens1/theano_pmb . It's definitely not professionally maintained, but all the changes needed are provided, so that Theano with full GPU support works today. I hope it can help others, and keep Theano alive.