The best I have been able to come up with is
ifconfig eth2 down && udevadm trigger -s net -a address="68:f7:28:1b:31:b5" -c add && systemctl restart NetworkManager.service
That will work if the interface name is currently eth2 and you have a rule like
SUBSYSTEM=="net", ACTION=="add", DRIVERS=="?*", ATTR{address}=="68:f7:28:1b:31:b5", ATTR{dev_id}=="0x0", ATTR{type}=="1", NAME="eth3"
So you get a interface named eth3 and NetworkManager is running.