Yes, you're not alone — I ran into this exact problem when upgrading from DevExpress 22.1.13 to 22.2.15 in a large WinForms application targeting .NET Framework 4.8.

Originally, I upgraded specifically to resolve DPI scaling problems (blurry fonts, layout inconsistencies at 125%+ scaling on Windows 10/11). The upgrade to 22.2.15 definitely improved DPI behavior, so that part worked great.