I had the issue where I could launch a browser and create a new profile but I couldn't reopen the browser with the new profile directory specified. I also found that I didn't have permissions to delete or modify the profile directory I just created. I had to restart my computer in safe mode and then limit the directory permissions to control by just my username (eliminating System and other admins control - which didn't matter for my personal computer) as well as limit the permissions of the chrome application folder (which was writing and adding permissions to the profile folder,) to just control by my username. Then once I restarted the computer normally, I was able to modify the chrome profile folders and properly launch and relaunch the same profile with selenium webdriver.