Yes. You can run a Unity VR project without a headset using OpenXR, the XR Interaction Toolkit, and the Meta XR Simulator. The Meta XR Simulator provides virtual input and simulated head and hand tracking, allowing you to test interactions directly in the Unity Editor. To do this, enable OpenXR with Meta XR as a feature group, add the Meta XR Simulator feature, and run the scene in Play Mode, no headset required.